Doctor's Best 5-HTP 100mg

60 vcaps
Doctor's Best, Doctors Best, 5-HTP, Tasman Health, Sleep, Mood Regulation

5-HTP is a natural derivative of the amino acid tryptophan and a precursor to the neurotransmitter serotonin. Serotonin is found in the synapses between neurons, responsible for regulating hunger, mood, and sleep. 5-HTP benefits mental and emotional health, as well as normal sleep periods. Doctor’s Best 5-HTP is derived from pure and natural Griffonia simplicifolia seeds.

Supplement Facts

Serving Size: 1 Capsule
Servings Per Container: 60


Amount Per Serving

% Daily Value

5-hydroxy L-tryptophan

100 mg


† Daily Value not established.

Other Ingredients: Modified cellulose (vegetarian capsule), microcrystalline cellulose, silicon dioxide.

Doctor's Best 5-HTP is tested to ensure that it does not contain "Peak X"

Suggested Use

Take 1 capsule daily, with or without food, or as recommended by a nutritionally-informed physician.


Not to be used when taking MAO inhibitors, selective serotonin reuptake inhibitors (SSRIs), or other anti-depressant medications. It should also not be used by individuals taking any of the category of medications known as "triptans". Keep out of reach of children.


5-HTP is an active compound essential to maintain mental and emotional health. Adequate 5-HTP dosage prevents serotonin deficiency and its negative effects on mental and emotional health. Low serotonin levels of serotonin in the brain have been directly linked to depression. Other symptoms of serotonin deficiency includes anxiety, insomnia, chronic fatigue syndrome, impaired cognitive functions, low-self esteem, and decreased interest to participate in daily activities. However, with adequate serotonin supply, an individual is likely to have an enhanced mood, positive outlook in life, since it is known to be the “feeling good” neurotransmitter. By ensuring healthy serotonin levels, 5-HTP also promotes normal sleep periods and rest, which allows the important organs of the body to revitalise their functions. 5-HTP supplements can also be used to achieve relaxation periods, a little time away from the noise and stress of a busy life. Some people use 5-HTP supplements as weight loss supplements. By promoting adequate sleep, 5-HTP prevents sleep-deprived induced binge eating.

5-Hydroxy L-Tryptophan, or simply 5-HTP is a naturally occurring derivative of the amino acid tryptophan, and also serves as precursor to the “feel-good” neurotransmitter serotonin. Tryptophan, an essential amino acid commonly found in milk, is metabolized into 5-HTP in the body. On the other hand, 5-HTP is actively converted into serotonin. When there is more 5-HTP available in the body, there are more building blocks for more serotonin production. Normally, synthesis of serotonin depends on the supply of tryptophan from the diet. However, this doesn’t guarantee adequate serotonin levels since it will depend on the individual’s nutritional status plus tryptophan competes with other amino acids to cross the blood-brain barrier. If tryptophan molecules are unlucky with the blood-brain barrier transport, they will be involved in the production of other compounds like niacin or protein. This is where 5-HTP is better at, it has the ability to easily cross the blood brain barrier and make itself readily available for synthesis of the “feel good” neurotransmitter serotonin. Conventional treatment for depression involves the use of SSRI (Selective Serotonin Reuptake Inhibitor) medications, which are aimed to increase serotonin levels circulating in the brain. Increasing serotonin production is also the direct effect of 5-HTP supplements like Doctor’s Best 5-HTP.