NOW Foods TMG 1000mg

100 tablets
Now Foods TMG 1000mg

Trimethylglycine or betaine is a methyl donor, a substance that can support the methylation processes occurring inside the body. Methylation is considered essential for DNA repair in the cells, liver detoxification, metabolism of lipids, and production of SAMe. TMG can also aid in the conversion of the damaging amino acid homocysteine into the beneficial amino acid methionine.

Supplement Facts

Serving Size: 3 Tablets
Servings Per Container: 33


Amount Per Serving

% Daily Value

Trimethylglycine (TMG)

(Betaine Anhydrous)

3.0g (3,000mg)


† Daily Value not established.

Other Ingredients: Cellulose, stearic acid (vegetable source), croscarmellose sodium, magnesium stearate (vegetable source) and vegetarian coating.

Suggested Use

Take 1 to 3 tablets twice daily, preferably with food.


For adults only. Consult Doctor if pregnant / nursing, taking medication, or have a medical condition.


  • Trimethylglycine can support healthy levels of the amino acid homocysteine in the body. Homocysteine is a naturally occurring “building block of protein” that in high levels increases the risk for cardiovascular diseases and stroke. People with low Vitamin B levels are at risk for elevated homocysteine and can therefore b recommended to take TMG supplements by health professionals to achieve homocysteine balance.
  • Trimethylglycine can possibly benefit people born with homocystinuria, a hereditary condition characterised by the inability to breakdown homocysteine. Now Foods TMG may aid in neutralising the toxic levels of homocysteine in the blood in homocystinuria. Supplementing with trimethylglycine has been shown to reduce the symptoms of homocystinuria such as eye lens dislocation, chronic fatigue, seizures, abnormal bone development and weak bones, and blood clot formations. Homocystinuria patients are also at higher risk of developing heart diseases as early as 20 years of age.
  • In animal studies, Trimethylglycine has demonstrated protective properties for the liver. TMG has been shown to reduce fatty liver deposits associated with chronic alcoholism, obesity, low protein intake, and diabetes.
  • Because it naturally increases the production of SAMe or S-adenosyl methionine, Trimethylglycine may help support a positive in depression. The brain can use SAMe to increase the availability of the mood-regulating neurotransmitters serotonin and dopamine. SAMe can be used as a raw material to produce more serotonin and dopamine to elevate mood in depressed patients.

Trimethyglycine (TMG) also known as Betaine is a naturally occurring substance in the body that works as a methyl donor. As a methyl donor, TMG donates methyl molecules to facilitate many different methylation processes involved in DNA repair, cell reproduction, mood regulation, lipid metabolism, cardiovascular disease prevention, homocystinuria treatment, and liver detoxification. Trimethylglycine is also found in sugar beets, grains, spinach, and shellfish.

As a methyl donor, Trimethylglycine can benefit the body’s homocysteine levels. Homocysteine is a non-protein amino acid naturally occurring in the body and also acquired from constantly consuming meat in the diet. This building block of protein can be irritating to the blood vessels and is strongly associated with arterial inflammation and hardening of the arteries. Through this, high homocysteine levels are major risk for cardiovascular diseases and stroke. Experts established the link between low levels of methyl donors such as Trimethyglycine and Vitamin B9 or Folic acid with high levels of homocysteine. Toxic homocysteine levels also occur with high levels of copper and mercury.